Tuesday 11 October 2011

1P24: v) Asymmetric aldol condensation as a route to polypropionate derived pheromones


J. P. DiBattista and F. X. Webster61 developed a new route for polypropionate derived pheromones using asymmetric aldol condensation as the key step for the synthesies of 129 and 134 as shown in scheme 24a and 24b following the procedure of Evans.62
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61. J. P. DiBattista, and F. X. Webster, Bioorg. Med. Chem., 1996, 4, 423.
62. D. A. Evans, R. L. Dow, T. L. Shih, J. M. Takas, and R. Zahler, J. Am. Chem. Soc., 1990, 112, 5290.
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